Words or phrases can be emphasised by using the <em> and <strong> elements. For example:
<p>I believe the Dave Raggett book is <em>really</em> good. Phone me <strong>after lunch</strong> please. <em>Really urgent that I <strong>talk</strong> to you!</em></p>
which would appear as
I believe the Dave Raggett book is really good. Phone me after lunch please. Really urgent that I talk to you!